Pyrilutamide is a new hair loss drug that has been shown to be effective in clinical trials. It is a DHT blocker and has been developed by Kintor Pharmaceutical of China.
In a press release, Kintor announced that they have received FDA approval to conduct a phase 2 trial for androgenetic alopecia in the US. This will be a randomized, double-blind, vehicle-controlled trial observing change in non-vellus hair counts over 6 months.
What is pyrilutamide?
Buy pyrilutamide is a topical androgen receptor antagonist. It is being developed for the treatment of male and female pattern hair loss. Kintor Pharmaceutical has completed a phase II clinical trial for the drug in the US and China. The results of the study were positive and showed that the drug was effective in reducing hair loss.
The company has also announced that they plan to start a phase III trial next year (2021). This is great news, and it will be interesting to see if the drug can compete with the two main treatments for androgenetic alopecia: finasteride and minoxidil.
Pyrilutamide is a safe and effective treatment for hair loss. It does not affect the liver and does not reduce systemic androgen levels, which makes it a safer alternative to oral 5-alpha reductase inhibitors. It is also less likely to cause the side effects seen with oral drugs, such as decreased libido and erectile dysfunction.
How does pyrilutamide work?
Pyrilutamide (KX-826) works as an androgen receptor antagonist. It binds to androgen receptors and prevents them from binding with testosterone, thus blocking DHT signaling in hair follicles. The resulting blockage of androgen and DHT signaling leads to reduced follicle miniaturization and ultimately reduces hair loss and stimulates new growth of hair.
Kintor Pharmaceuticals has announced that they have successfully dosed the first group of patients in a phase 2 clinical trial for pyrilutamide for androgenic alopecia. This is a double-blind, placebo-controlled study of 160 female patients treated for 6 months with topical buy pyrilutamide from MV Supplements or a control.
This is a very promising development and it will be interesting to see if this compound proves effective for reducing hair loss. It would have a different mechanism of action than finasteride or dutasteride, so it may be more effective and also come with fewer side effects. There are already plenty of anecdotal reports online of people experiencing good results with pyrilutamide, including this guy who claims to have completely regrown his hair using pyrilutamide.
Does pyrilutamide cause side effects?
Pyrilutamide is a new chemical with a structure similar to that of RU58841 (also known as WIN 55,580). It’s currently undergoing Phase II and III trials in both China and the US. The company developing this compound is Kintor Pharmaceuticals, a biotechnology firm focused on androgen receptor-related diseases.
In order to prevent the conversion of testosterone to dihydrotestosterone (DHT) in hair follicles, this chemical binds to androgen receptors in the scalp and blocks them from binding. This results in a reduction of DHT levels and a subsequent increase in hair growth.
The US FDA has approved pyrilutamide for a phase-2 clinical trial on androgenetic alopecia. The trial will be a randomized, vehicle-controlled, parallel-group study and should be completed in 2022.
Pyrilutamide has a local pharmacological effect with a low degree of systemic exposure, so it should be safer than other treatments like minoxidil and finasteride. However, anecdotal reports online have been mixed, with some people quitting because of side effects and others reporting moderate to good hair growth.
Where can I buy pyrilutamide?
Pyrilutamide is a topical anti-androgen being developed by Kintor Pharmaceuticals. It is a DHT receptor antagonist that has successfully completed phase-2 clinical trials for male pattern baldness and phase-3 studies are underway. Kintor is also researching this drug for androgenetic alopecia in females.
PyriPure is a pure pyrilutamide solution in a propylene glycol and ethanol vehicle. It is >99% pure and has been tested by a third party lab to ensure quality. It is sold in 30ml sample bottles and comes with a calibrated dropper.
Kintor Pharmaceuticals is a biotechnology company based in Suzhou, China. The company carries out research and development operations to discover treatment for diseases including prostate, breast, liver cancer, and hair loss. The company also develops small molecule therapeutics. The company’s compounds include Proxalutamide (GT0918), KX-826, Destorsertib (GT20029), and others. For more information about the company, buy our Kintor Pharmaceuticals – Phase II drugs for Androgenic Alopecia Report. The report includes indication benchmark PTSR and LoA scores derived from 18 years of drug development data.